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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
15.45
Human Site:
Y447
Identified Species:
21.25
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
Y447
K
Q
T
I
P
H
Y
Y
L
S
I
D
V
N
M
Chimpanzee
Pan troglodytes
XP_522180
647
68973
Y447
K
Q
T
I
P
H
Y
Y
L
S
I
D
V
N
M
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
Y447
K
Q
T
I
P
H
Y
Y
L
S
I
D
V
N
M
Dog
Lupus familis
XP_546524
647
68802
Y447
K
Q
T
I
P
H
Y
Y
L
S
I
D
V
N
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
D446
P
H
Y
Y
L
S
V
D
V
N
M
G
E
V
L
Rat
Rattus norvegicus
P08461
632
67147
V437
H
Y
Y
L
S
V
D
V
N
M
G
E
V
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
L353
V
L
L
V
R
K
E
L
N
K
M
L
A
G
S
Chicken
Gallus gallus
XP_417933
681
72018
T476
R
L
M
Q
S
K
Q
T
I
P
H
Y
Y
L
S
Frog
Xenopus laevis
NP_001082239
628
66845
P424
M
Q
S
K
Q
T
I
P
H
Y
Y
L
S
I
D
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
I447
L
M
Q
S
K
Q
T
I
P
H
Y
Y
L
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
Y331
R
A
K
V
N
K
K
Y
E
K
Q
G
A
R
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
G326
L
N
G
L
L
A
K
G
T
S
G
Q
A
T
K
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
M306
L
Q
G
S
L
N
E
M
V
S
E
D
T
P
I
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
E331
S
Q
L
N
L
I
Q
E
T
S
G
G
K
R
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
E358
S
Q
L
N
S
F
K
E
A
S
G
G
K
R
I
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
D301
S
L
N
A
T
A
N
D
K
Y
K
L
S
I
N
Red Bread Mold
Neurospora crassa
P20285
458
48601
G277
A
L
N
S
S
A
D
G
R
Y
K
L
S
V
N
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
100
100
N.A.
0
6.6
N.A.
0
0
6.6
0
N.A.
6.6
N.A.
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
13.3
13.3
13.3
20
N.A.
26.6
N.A.
13.3
40
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
13.3
N.A.
N.A.
13.3
0
0
P-Site Similarity:
20
N.A.
N.A.
20
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
6
0
18
0
0
6
0
0
0
18
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
12
0
0
0
30
0
0
6
% D
% Glu:
0
0
0
0
0
0
12
12
6
0
6
6
6
0
0
% E
% Phe:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
0
12
0
0
24
24
0
6
0
% G
% His:
6
6
0
0
0
24
0
0
6
6
6
0
0
0
0
% H
% Ile:
0
0
0
24
0
6
6
6
6
0
24
0
0
12
24
% I
% Lys:
24
0
6
6
6
18
18
0
6
12
12
0
12
0
6
% K
% Leu:
18
24
18
12
24
0
0
6
24
0
0
24
6
12
12
% L
% Met:
6
6
6
0
0
0
0
6
0
6
12
0
0
0
24
% M
% Asn:
0
6
12
12
6
6
6
0
12
6
0
0
0
24
12
% N
% Pro:
6
0
0
0
24
0
0
6
6
6
0
0
0
6
0
% P
% Gln:
0
48
6
6
6
6
12
0
0
0
6
6
0
0
0
% Q
% Arg:
12
0
0
0
6
0
0
0
6
0
0
0
0
18
0
% R
% Ser:
18
0
6
18
24
6
0
0
0
48
0
0
18
6
12
% S
% Thr:
0
0
24
0
6
6
6
6
12
0
0
0
6
6
0
% T
% Val:
6
0
0
12
0
6
6
6
12
0
0
0
30
12
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
12
6
0
0
24
30
0
18
12
12
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _